The Horvitz lab reports on an interesting model of hypoxia-reoxygenation in C. elegans.  During the reoxygenation period worms thrash about at a high rate and this effect is suppressed by mutations in worm HIF-1.  Thrashing is restored by a gof mutation in a cytochrome P450 gene and seems to involve the production of specific lipid mediators from worm PUFA stores.  Interesting model and result.