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Publications


 

 

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Publications


 

 

#Dixon lab member names are bolded.


2018

Magtanong L, Ko P-J, To M, Cao JY, Tarangelo A, Ward CC, Cho KY, Patti GJ, Nomura DK, Olzmann JA, Dixon SJ. Exogenous monounsaturated fatty acids suppress non-apoptotic cell death. Submitted (Cell Press Sneak Peak: https://www.mendeley.com/sneak-peek/cellpress/#3ce05cce-3a0f-4564-a905-8668bb604666).

Dovey C, Diep J, Clarke BP, Hale AT, McNamara DE, Guo H, Brown Jr NW, Cao JY, Grace CR, Gough PJ, Bertin J, Dixon SJ, Fiedler D, Mocarski ES, Kaiser WJ, Moldoveanu T, York JD, Carette JE. (2018). MLKL requires the inositol phosphate code to execute necroptosis. Molecular Cell 70: 936-948.

Tarangelo A, Dixon SJ. The p53-p21 pathway inhibits ferroptosis during metabolic stress. (2018) Oncotarget 9:24572-24573.

Inde Z, Dixon SJThe impact of non-genetic heterogeneity on cancer cell death. (2018). Critical Reviews in Molecular & Cell Biology 53: 99-114. [Link][PubMed]

Galluzzi L, Vitale I,...[many authors]...Dixon SJ,...[many authors]...Melino G, Kroemer G. (2018). Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. Cell Death & Differentiation 25: 486-541. [PubMed]

Tarangelo A, Magtanong LBieging-Rolett KT, Li Y, Ye J, Attardi L, Dixon SJ. (2018). p53 suppresses metabolic stress-induced ferroptosis in cancer cells. Cell Reports 22: 596-575. [pdf][PubMed][Faculty of 1000][Commentary by Kris Sarosiek in Sci Transl Med]

 

2017

Stockwell BR, Angeli JPF, Bayir H, Ashley I. Bush, Conrad M, Dixon SJ, Fulda S, Gascon S, Hatzios SK, Kagan V, Noel K, Jiang X, Linkermann A, Murphy ME, Overholtzer M, Oyagi A, Pagnussat G, Park J, Prives C, Ran Q, Rosenfeld CS, Salnikow K, Tang D, Torti F, Torti S, Toyokuni S, Woerpel KA, Zhang DD. Ferroptosis: a regulated cell death nexus linking metabolism, redox biology, and disease. (2017). Cell 171: 273-285. [pdf][PubMed]

Forcina GC, Conlon M, Wells A, Cao J-YDixon SJ. (2017). Systematic quantification of cell death kinetics in mammalian cells. Cell Systems 4: 600-610. [pdf][PubMed][Commentary by Li & Yuan in Cell Chem Biol]

Conlon M, Dixon SJ. (2017). Ferroptosis-like cell death in plants. Molecular & Cellular Oncology 4:e1302906. [PubMed]

Dixon SJ. (2017). Ferroptosis: bug or feature? (2017). Immunological Reviews 227: 150-157.  [pdf][PubMed]

Distéfano AM, Martin MV, Córdoba JP,  Bellido AM,D’Ippólito S,  Colman SL,  Soto D, Roldán JA,  Bartoli CG, Zabaleta EJ,  Fiol DF,  Stockwell BR,  Dixon SJ^, Pagnussat GC^. (2017). Heat stress induces ferroptosis-like cell death in plants. Journal of Cell Biology 216:463-476. [Pubmed]
^Co-corresponding author

 

2016

Tarangelo A, Dixon SJ. (2016). An iron age for cancer therapy. Nature Nanotechnology 11:921-922. [Pubmed]

Magtanong L, Ko PJ, Dixon SJ. (2016). Emerging roles for lipids in non-apoptotic cell death. Cell Death & Differentiation. Mar 11, doi: 10.1038. [pdf][PubMed]

Cao J-Y, Dixon SJ. (2016). Mechanisms of ferroptosis. Cellular and Molecular Life Sciences. doi: 10.1007. [pdf][PubMed]

Shimada K, Skouta R, Kaplan A, Yang WS, Hayano M, Dixon SJ, Brown LM, Valenzuela CA, Wolpaw AJ, Stockwell BR. (2016). Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis. Nature Chemical Biology 12:497503. [PubMed]

 

2015

Dixon SJ^*, Winter GE*, Musavi LS, Lee E", Snijder B, Rebsamen M, Superti-Furga G^, Stockwell BR^. (2015).  Human haploid cell genetics reveals roles for lipid metabolism in non-apoptotic cell death. ACS Chemical Biology 10:1604-1609. [PubMed]
^Co-corresponding author
*Equal contribution

Jacunski A, Dixon SJ, Tatonetti NP. (2015). Connectivity Homology Enables Inter-Species Network Models of Synthetic Lethality. PLoS Computational Biology. Oct 9;11(10):e1004506. [PubMed]

 

2014

Dixon SJ^, Stockwell BR^. (2014). The role of iron and reactive oxygen species in cell death. Nature Chemical Biology 10: 9-17. [pdf] [PubMed]
^Co-corresponding author

Dixon SJ*, Patel DN*, Welsch M, Skouta R, Lee ED, Hayano M, Thomas AG, Gleason C, Tatonetti N, Slusher BS, Stockwell BR. (2014). Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis. eLife 20;3e02523. [PubMed]
*Equal contribution

Skouta R, Dixon SJ, Wang JDunn DEOrman MShimada KRosenberg PALo DCWeinberg JMLinkermann AStockwell BR. (2014). Ferrostatins inhibit oxidative lipid damage and cell death in diverse disease models. JACS 136: 4551-4556 [PubMed]

 


Scott's previous worK

Dixon SJ, Lemberg KM, Lampretch MR, Skouta R, Zaitsev EM, Gleason CM, Patel DN, Bauer AJ, Cantley AM, Yang WS, Morrison III B, Stockwell BR. (2012). Ferroptosis: A non-apoptotic form of iron-dependent cell death. Cell 149: 1060-1072. [pdf] [PubMed]

Ho CH, Piotrowski J, Dixon SJ, Baryshnikova A, Costanzo M, Boone C. (2011). Combining functional genomics and chemical biology to identify targets of bioactive compounds. Curr Opin Chem Biol 15: 66-78. [pdf] [PubMed]

Dixon SJ, Stockwell BR. (2010). Drug discovery: engineering drug combinations. Nat Chem Biol 6: 318-9.  [pdf] [PubMed]

Baryshnikova A, Costanzo M, Dixon S, Vizeacoumar FJ, Myers CL, Andrews B, Boone C. (2010). Synthetic genetic array (SGA) analysis in Sacharromyces cerevisiae and Schizosaccharomyces pombe. Methods Enzymol 470: 145-179. [pdf] [PubMed]

Dixon SJ*, Constanzo MJ*, Baryshnikova A, Andrews BA, Boone CB. (2009). Systematic mapping of genetic interaction networks.  Ann Rev Genet 43: 601-25. [pdf] [PubMed]
*Equal contribution

Dixon SJ, Andrews B, Boone C. (2009). Exploring the conservation of synthetic lethal genetic interaction networks. Commun Integr Biol 2: 1-4. [pdf] [PubMed]

Dixon SJ, Stockwell BR. (2009). Identifying disease-modifying druggable gene products.  Curr Opin Chem Biol 13:549-55. [pdf] [PubMed]

Alexander M, Chan KK, Byrne AB, Selman G, Lee T, Ono J, Wong E, Puckrin R, Dixon SJ, Roy PJ. (2009). An UNC-40 pathway directs postsynaptic membrane extension in Caenorhabditis elegansDevelopment 136: 911-22. [pdf] [PubMed]

Dixon SJ*, Fedyshyn Y*, Koh JL*, Prasad TS, Chahwan C, Chua G, Toufighi K, Baryshnikova A, Hayles J, Hoe KL, Kim DU, Park HO, Myers CL, Pandey A, Durocher D, Andrews BJ, Boone C. (2008). Significant conservation of synthetic lethal genetic interaction networks between distantly related eukaryotes. Proc Natl Acad Sci 105: 16653-8. [pdf] [PubMed]
*Equal contribution

Dixon SJ*, Alexander M*, Chan KK, Roy PJ. (2008). Insulin-like signaling negatively regulates muscle arm extension through DAF-12 in Caenorhabditis elegans. Dev Biol 318: 153-61. [pdf] [PubMed]
*Equal contribution

Byrne AB, Weirauch MT, Wong V, Koeva M, Dixon SJ, Stuart JM, Roy PJ. (2007). A global analysis of genetic interactions in Caenorhabditis elegans. J Biol 6:8. [pdf] [PubMed]

Dixon SJ, Alexander M, Fernandes R, Ricker N, Roy PJ. (2006). FGF negatively regulates muscle membrane extension in Caenorhabditis elegans. Development 133: 1263-1275. [pdf] [PubMed]

Dixon SJ*, MacDonald JI*, Robinson KN, Kubu CJ, Meakin SO. (2006). Trk receptor binding and neurotrophin/fibroblast growth factor (FGF)-dependent activation of the FGF receptor substrate (FRS)-3. Biochim Biophys Acta 1763: 366-80. [pdf] [PubMed]
*Equal contribution

Dixon SJ, Roy PJ (2005). Muscle arm development in Caenorhabditis elegans. Development 132: 3079-3092. [pdf] [PubMed]

Dixon SJ, Persinger MA. (2001). Suppression of analgesia in rats induced by morphine or L-NAME but not both drugs by microtesla, frequency-modulated magnetic fields. International Journal of Neuroscience 108: 87-97. [PubMed]

^Co-corresponding author
*Equal contribution